1315 Clinical application of lens autofluorescence
نویسندگان
چکیده
منابع مشابه
1315 Clinical application of lens autofluorescence
Background and purpose: A likely explanation for the increase in lens fluorescence with aging and the acceleration of this process in patients with diabetes, is that lens proteins are altered by non-enzymatic glycosylation and the further steps of the Maillard reaction. Thus, the lens fluorescence intensity appears to represent a cumulative index of glycemia over the entire lifetime of the subj...
متن کاملSimultaneous noninvasive clinical measurement of lens autofluorescence and rayleigh scattering using a fluorescence biomicroscope.
BACKGROUND Lens autofluorescence increases with the age of the subject, and the fluorophores responsible are associated with cataract, retinopathy, and other complications of diabetes. We built a scanning confocal lens fluorescence biomicroscope suitable for routine clinical measurement of lens autofluorescence and light scattering and report data from 127 healthy subjects. METHOD The fluores...
متن کاملDmd065326 1307..1315
Accurate determination of rates of de novo synthesis and degradation of cytochrome P450s (P450s) has been challenging. There is a high degree of variability in the multiple published values of turnover for specific P450s that is likely exacerbated by differences in methodologies. For CYP3A4, reported half-life values range from 10 to 140 hours. An accurate value for kdeg has been identified as ...
متن کاملDdh146 1315..1319
Department of Genetic Medicine, Women’s and Children’s Hospital, North Adelaide, South Australia, Australia, Department of Paediatrics and Department of Molecular Biosciences, University of Adelaide, South Australia, Australia, Departments of Neurology, Molecular Physiology and Biophysics and Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA, Epilepsy Research Instit...
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ژورنال
عنوان ژورنال: Vision Research
سال: 1995
ISSN: 0042-6989
DOI: 10.1016/0042-6989(95)90073-x